Influenza A/B Inhibitor

Program Discovery Preclinical Phase 1 Phase 2a Phase 3
Influenza Influenza A/B Inhibitor
Discovery Phase in progress
Preclinical Phase not started
Phase 1 Phase not started
Phase 2a Phase not started
Phase 3 Phase not started

We are developing another class of influenza antivirals targeting influenza polymerase complex (PB1:PB2:PA) for the treatment of influenza A and B infections. We are currently improving antiviral potency and drug-like properties of the influenza A/B dual inhibitors.

We are currently engaged in an exclusive license and collaboration agreement with Merck Sharp & Dohme Corp. (“Merck”) to discover and develop certain proprietary influenza A/B antiviral agents.

Under the terms of the agreement, Merck will fund all research and development for the program, including clinical development, and will be responsible for worldwide commercialization of any products derived from the collaboration. Cocrystal was paid a $4 million upfront license fee and is eligible to receive payments related to designated development, regulatory and sales milestones with the potential to earn up to $156 million, plus undisclosed royalties on product sales.