We are a clinical-stage biotechnology company developing novel therapeutics to meet the growing global need for effective, safe antiviral treatments.  We employ a unique structure-based drug discovery technology platform and Nobel Prize-winning expertise to create first- and best-in-class antiviral drugs.  Our antivirals target the replication process and are designed to be safe, broad-spectrum, resistant and convenient to administer.

We are quickly and efficiently advancing multiple programs with clinical development underway for influenza, norovirus and coronaviruses, while also discovering and developing antiviral compounds for other high-value indications.

Targeted Solutions for Viral Diseases

Novel antiviral therapeutics for the treatment of serious and/or chronic viral diseases including influenza, COVID-19, hepatitis C and gastroenteritis caused by norovirus.

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About Us

Cocrystal Pharma, Inc. is a clinical-stage biotechnology company discovering and developing novel antiviral therapeutics that target the replication process of influenza virus, SARS-CoV-2 virus, hepatitis C virus, and norovirus.

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Technology

We utilize unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs.

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Development Programs

Our development programs include a wide variety of serious and/or chronic viral diseases including influenza, COVID-19, hepatitis C and gastroenteritis caused by norovirus.

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Program Discovery Preclinical Phase 1 Phase 2 Phase 3
Norovirus Oral Pan-viral protease Inhibitor CDI-988
Discovery Phase complete
Preclinical Phase complete
Phase 1 Phase in progress
Phase 1 complete
Phase 1b to begin in H1 2026
Phase 2 Phase not started
Phase 3 Phase not started
Phase 1 complete
Phase 1b to begin in H1 2026
Coronavirus Oral Pan-viral protease Inhibitor CDI-988
Discovery Phase complete
Preclinical Phase complete
Phase 1 Phase in progress
Phase 1 complete
Phase 2 Phase not started
Phase 3 Phase not started
Phase 1 complete
Rhinovirus Pan-viral protease inhibitor
Discovery Phase complete
Preclinical Phase in progress
Lead discovery ongoing
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
Lead discovery ongoing
Influenza A Oral PB2 inhibitor CC-42344
Discovery Phase complete
Preclinical Phase complete
Phase 1 Phase complete
Phase 2 Phase in progress
Phase 2a challenge study complete
Phase 3 Phase not started
Phase 2a challenge study complete
Influenza A Inhaled PB2 inhibitor CC-42344
Discovery Phase complete
Preclinical Phase complete
GLP tax study complete
Phase 1 Phase complete
Phase 2 Phase complete
Phase 3 Phase complete
GLP tax study complete
Influenza A & B Oral replication inhibitor
Discovery Phase complete
Preclinical Phase in progress
Lead discovery ongoing NIH SBIR Funded
Phase 1 Phase not started
Phase 2 Phase not started
Phase 3 Phase not started
Lead discovery ongoing NIH SBIR Funded

Investor Presentation

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